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ANTIMICOBIALS, ANTIINFECTIVE
Amoxicillin (Amoxil
® )
Semisynthetic analog of ampicillin
Indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative)
strains of the designated microorganisms in the conditions listed below:
-
Ear, nose, and throat infection due to Streptococcus spp. (α- and β-hemolytic
strains only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.
Mild to moderate infection:
500 mg every 12 hours OR 250 mg every 8 hours
Severe infection:
875 mg every 12 hours OR 500 mg every 8 hours
- Lower respiratory tract infection due to Streptococcus spp. (α- and β-hemolytic
strains only), Streptococcus pneumoniae, Staphylococcus spp., or H. influenzae
Mild , moderate, or severe infection:
875 mg every 12 hours OR 500 mg every 8 hours
- Skin or skin structure infection due to
Streptococcus spp. (α- and β-hemolytic strains only), Streptococcus pneumoniae, Staphylococcus spp., or
Haemophilus influenzae.
Mild to moderate infection:
500 mg every 12 hours OR 250 mg every 8 hours
Severe infection:
875 mg every 12 hours OR 500 mg every 8 hours
- Genitourinary tract infection due to Escherichia coli, Proteus mirabilis, or Enterococcus faecalis
Mild to moderate infection:
500 mg every 12 hours OR 250 mg every 8 hours
Severe infection:
875 mg every 12 hours OR 500 mg every 8 hours
- Gonorrhea, acute uncomplicated (ano-genital and urethral infections) due to
N. gonorrhoeae (males and females)
3 grams as asingle oral dose
- Helicobacter pylori eradication to reduce the risk of duodenal ulcer recurrence
Triple therapy: Amoxil/clarithromycin/lansoprazole
1 gram Amoxil, 500 mg clarithromycin, and 30 mg
lansoprazole, all given twice daily (q12h) for 14 days.
Dual therapy: Amoxil/lansoprazole
1 gram Amoxil (amoxicillin) and 30 mg lansoprazole,
each given three times daily (q8h) for 14 days.
- Endocarditis prophylaxis for dental, oral,
respiratory tract, or esophageal procedures in adult:
2.0 g given orally one hour before procedure
Patients severely impaired renal function (glomerular filtration rate of <30 mL/minute) should not receive the 875-mg tablet.
Amoxil chewable tablets contain phenylalanine and should not be used by phenylketonurics.
(250 , 500 mg capsules; 500 , 875 mg tablets; 200 , 400 mg chewable
tablets; 200 mg / 5 mL suspension (50, 75, 100 mL bottles), 250 mg / 5 mL suspension
(100,150 mL bottles), and 400 mg/ 5mL suspension (50, 75, 100 mL bottles).)
Pregnancy Category B
Use in
Pregnancy
Ampicillin(®)
(2mg capsules)
Pregnancy
Category
Azithromycin
(Zithromax ®)
Azithromycin is an azalide antibiotic related to erythromycin
- Acute bacterial exacerbations of
COPD
due to Haemophilus influenzae, Moraxella catarrhalis or
Streptoccocus pneumoniae:
500 mg daily X 3 days OR 500 mg as a single dose on
Day 1, followed by 250 mg once daily on Days 2 through 5.
-
Acute bacterial sinusitis due to Haemophilus influenzae, Moraxella catarrhalis orStreptoccocus
pneumoniae:
500 mg daily X 3 days
- Community-acquired pneumonia due to
Chlamydia pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae or
Streptoccocus pneumoniae in patients approprite for oral therapy:
500 mg
single dose on Day 1, followed by 250 mg once daily Days 2 through 5.
- Pharyngitis/tonsillitis caused by Streptococcus pyogenes as
an alternative to penicillin:
500 mg single dose on Day 1, followed by 250 mg once daily Days 2 through 5.
- Uncomplicated skin infections due to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus
agalactiae:
500 mg single dose on Day 1, followed by 250 mg once daily Days 2 through 5.
-
Urethritis or cervicitis due to Chlamydia trachomatis or Neisseria gonorrhea:
One single 1 gram dose.
( 250 mg tablet ( Package of 6 "Z-Pak"), 500 mg tablet(package
of 3 Tri-Pak); 100 mg / 5 mL suspension (15 mL bottle), 200 mg / 5 mL
suspension (15, 22.5, 30mL bottles)
Pregnancy Category B
Use in Pregnancy
Cefazolin(®)
(2mg capsules)
Pregnancy
Category
Ceftriaxone(®)
(250 , 500 mg capsules)
Pregnancy
Category
Cephalexin(®)
(250 , 500 mg capsules)
Pregnancy
Category
Ciprofloxacin(Cipro ®)
(250 , 500 mg capsules)
Pregnancy
Category
Clarithromycin ( ®)
( )
Pregnancy
Category
Clindamycin (Cleocin ®)
( )
Pregnancy
Category
Doxycycline (Vibramycin ®)
(250 , 500 mg capsules)
Pregnancy
Category
Erythromycin(®)
(250 , 500 mg capsules)
Pregnancy
Category
Metronidazole(Flagyl ®)
(250 , 500 mg capsules)
Pregnancy
Category
Trimethoprim-sulfamethoxazole(Bactrim ®)
(250 , 500 mg capsules)
Pregnancy
Category |
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