Yellow Fever Vaccine in Pregnancy and Breastfeeding
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Vaccine, Yellow Fever
Live attenuated virus vaccine.

Robert E, et al. reported on women who had received yellow fever vaccine (YFV) during early pregnancy. Of 58 pregnancies with completed follow-up five ended in voluntary abortions, seven in spontaneous abortion, and  46 births. Three newborns had minor anomalies and two had major defects (ureteral stenosis and triphalangeal hallux)[1].

Women who must travel to areas where the risk of yellow fever is high should be vaccinated. However if a travel requirement is the only reason for vaccination, then efforts should be made to obtain a waiver letter from the travelerís physician [2].

BREAST FEEDING: Compatible [3, 4].


1. Robert E , et al.,Exposure to yellow fever vaccine in early pregnancy. Vaccine. 1999 ;17:283-5.MEDLINE
2. Centers for Disease Control & Prevention. Yellow Fever Vaccine: Recommendations of the Immunization Practices Advisory Committee (ACIP). MMWR 39 (No. RR-6): 3, 1990.
3. Centers for Disease Control & Prevention. General Recommendations on Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 43 (No. RR-1): 20-21, 1994.
4.Breastfeeding and Maternal Medication. Recommendations for Drugs in the Eleventh WHO Model list of Essential Drugs. pp 23-24 World Health Organization, 2002. 20 Avenue Appia ,1211 Geneva ,Switzerland
(PDF file)

Created: 11/27/2002
Last Update: 11/30/2003

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