Yellow Fever Vaccine
in Pregnancy and Breastfeeding
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Drugs in Pregnancy
> Yellow Fever Vaccine
Live attenuated virus vaccine.
Robert E, et al. reported on women who had received yellow fever
vaccine (YFV) during early pregnancy. Of 58 pregnancies with completed follow-up five ended in voluntary abortions, seven in spontaneous abortion, and 46 births. Three newborns had minor anomalies and two had
major defects (ureteral stenosis and triphalangeal hallux).
Women who must travel to areas where the risk of yellow fever is high should be vaccinated. However if
a travel requirement is the only reason for vaccination, then efforts should be made to obtain a waiver letter from the travelerís physician .
BREAST FEEDING: Compatible [3, 4].
1. Robert E , et al.,Exposure to yellow fever vaccine in early pregnancy. Vaccine. 1999 ;17:283-5.MEDLINE
2. Centers for Disease Control & Prevention. Yellow Fever Vaccine: Recommendations of the
Immunization Practices Advisory Committee (ACIP). MMWR 39 (No. RR-6): 3, 1990.
3. Centers for Disease Control & Prevention. General Recommendations on Immunization:
Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 43 (No.
RR-1): 20-21, 1994.
4.Breastfeeding and Maternal Medication.
Recommendations for Drugs in the Eleventh WHO Model list of Essential Drugs. pp
23-24 World Health Organization, 2002. 20 Avenue Appia ,1211 Geneva ,Switzerland
Last Update: 11/30/2003
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