in Pregnancy and Breastfeeding
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Drugs in Pregnancy
Loperamide (Imodium A-DŽ)
Antidiarrheal Agent. Molecular weight: 513.5
The use of loperamide during pregnancy was not associated with an increased
risk of major malformations in a study of 89 women exposed to loperamide in the first trimester of
However, of women who took loperamide throughout their pregnancy, 21 of 105 had
babies who were 200 g smaller than babies in the control group .
BREAST FEEDING: Compatible 
Briggs GG,Freeman RK, Yaffe SJ, Drugs in Pregnancy
and Lactation 6th edition,Baltimore, MD:
2.Einarson A,et al. Prospective, controlled, multicentre study of
loperamide in pregnancy.Can J Gastroenterol. 2000 Mar;14(3):185-7. PMID: 10758415
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