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 What is the risk of HELLP syndrome recurring?

HELLP is an acronym that describes the syndrome of :

H Hemolysis; EL elevated liver enzymes; LP, low platelets.

HELLP syndrome is considered to be a variant of preeclampsia. However, unlike preeclampsia hypertension and proteinuria do not need to be present for the diagnose HELLP syndrome.

Patients who have had HELLP syndrome have a 5 to 27 percent risk of developing HELLP syndrome and up to a 43 percent risk of developing preeclampsia in subsequent pregnancies [1-3].


Sullivan CA,et al., The recurrence risk of the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP) in subsequent gestations. Am J Obstet Gynecol 1994;171:940-3 PUBMED

2.Chames MC, et al., Subsequent pregnancy outcome in women with a history of HELLP syndrome at < or = 28 weeks of gestation.Am J Obstet Gynecol. 2003;188:1504-7 PUBMED

3.Sibai BM et al., Pregnancies complicated by HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): subsequent pregnancy outcome and long-term prognosis.Am J Obstet Gynecol.1995;172(1 Pt 1):125-9. PUBMED

Created: 12/15/2005


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